WT1 and neoplasm: Among the tested cases, the authors also identified one patient carrying a FBXW7 heterozygous germline mutation (c.45_46insCCT) impairing only the α-isoform of the transcripts, but the coexistence of another germline mutation in WT1 in the patient hampered any consideration about the contribution of the FBXW7 alteration to tumor predisposition.