Immunosuppressive therapy with cyclosporine and sirolimus (a mTOR inhibitor) was continued until the age of 32, when a Stage I WT of the naïve right kidney was diagnosed (triphasic nephroblastoma without anaplasia; at immunocytochemical analysis, WT1 was focally expressed at nuclear level by neoplastic cells) and treated by nephrectomy and adjuvant chemotherapy with actinomycin D and vincristine. Here, MTOR is linked to Nephroblastoma.