Mutations in BRCA1, BRCA2, and PALB2 could be implicated because of the young age of onset of breast cancer; while BRCA1 mutations are not associated with WT or Hodgkin’s lymphoma (HL), bi-allelic mutations of BRCA2 and PALB2 cause Fanconi Anemia type D1 and Fanconi anemia type N, respectively, of which WT is an associated clinical feature. The gene discussed is PALB2; the disease is breast carcinoma.