In 2000, Hoffman et al.15reported a single suspicious HPV positive sample in a group of 33 nasal polyp patients by using SBH and qualitative PCR, while Zaravinos et al.,10 utilizing qualitative PCR (GP5+/6+ non-type-specific primers), found a non significant presence of HPV in CRSwNP patients (3/23, 13%) compared to their controls (0/13 inferior turbinates). Here, GP5 is linked to Nasal polyposis.