MMP9 and carcinoma: Expression of LMP1 in rodent fibroblast and epithelial carcinoma cell lines promotes cell growth and motility.4, 6 LMP1 regulates cell motility by the modulation of junctional proteins including plakoglobin and E-cadherin, secretion of the matrix metalloproteinase 9 and potentially through the induction of N-cadherin.7, 8, 10, 11, 14, 19, 34, 35 In this study, LMP1-mediated effects on cell surface interactions were further evaluated for integrin and cadherin-mediated interactions in the pre-malignant cell line MCF10a.