CXCL8 and asthma: Neutrophilic asthma is a distinct asthmatic phenotype with poor therapeutic response and a lack of mechanistic insights.1 In these patients, neutrophil numbers and their secretory products, such as CXCL8, neutrophil elastase (NE) and matrix metalloproteinase (MMP)‐9, are elevated in the airways, particularly during exacerbation.