Xiang et al. [13] also showed that a multiple myeloma cell line with low FcγRIIB expression levels was resistant to apoptosis and that the susceptibility was restored when FcγRIIB surface expression was increased, indicating a link between the surface expression levels of FcγRIIB and the functional outcomes of crosslinking. The gene discussed is FCGR2B; the disease is plasma cell myeloma.