Multivarite Cox analyses also indicated that p-p38 expression (p < 0.05, HR = 2.93, 95 % CI 1.13–7.5) and Bcl-2 expression (p < 0.05, HR = 3.33, 95 % confidence interval 1.28–6.63) and the ABC subtype (p < 0.05, HR = 2.45, 95 % CI 1.68–4.56) to be independent factors associated with OS (Table 3). The gene discussed is BCL2; the disease is aneurysmal bone cyst.