PKR1 mRNA could be detected in all five NAG (3,148 ± 2,842 copies), nine out of ten ACC (227.8 ± 42.93 copies), and four out of five ACA (two cortisol-producing adenomas, one aldosterone-producing adenoma, one endocrine-inactive adenoma) (2,301 ± 2,110 copies) with the strongest expression in the aldosterone-producing adenoma (8,630 copies) (Fig. 1b). This evidence concerns the gene PROKR1 and adenoma.