SLC5A2 and type 2 diabetes mellitus: The effects of SGLT2 inhibitors on macrovascular and microvascular outcomes are yet to be determined in human studies; however, adding SGLT2 inhibitors, and specifically dapagliflozin, to the standard of care was recently projected to reduce cardiovascular and microvascular complications associated with T2DM, in a human model study using simulation methodology [34].