CD40 and systemic lupus erythematosus: The rs4810485 minor allele T is under-represented in SLE and correlates with reduced CD40 expression in peripheral blood monocytes and B cells, with potential implications for the regulation of aberrant immune responses in the disease, the CD40 gene rs4810485 G/T polymorphisms between the group of patients with SLE and the control group in European-American population (P < 0.05) [31].