The BioXpress database indicates that CMTM4 is downregulated in 95.83 % of ccRCC samples compared with their paired normal samples based on RNA sequencing (RNA-seq); the data set deposited in the Cancer Genome Atlas (TCGA) from a total of 128 patients has been collected and used for the analysis [40]. Here, CMTM4 is linked to nonpapillary renal cell carcinoma.