Combined treatment with ABT263 and TIC10/ONC201 results in a marked increase in the fraction of annexin V-positive (apoptotic) SF188 (pediatric - C), T98G (adult - D), MGPP-3 (transgenic proneural - E) and NCH644 (glioma stem-like - F) as well as NCH421K (glioma stem-like - Supplementary Figure 1) glioblastoma cells. This evidence concerns the gene ANXA5 and glioblastoma.