In order to identify KLF5 targets that directly participate in miR-375/KLF5-regulated tumor premalignant progression, we conducted an analysis comparing the 932 up-regulated genes with the 50 KLF5 target genes identified using QIAGEN's Ingenuity® Pathway Analysis (IPA®, QIAGEN Redwood City, http://www.qiagen.com/ingenuity). Here, KLF5 is linked to neoplasm.