STAT3 and neoplasm: The immunohistochemistry analysis of tumor section by hematoxylin and eosin staining and proliferation antigens against PCNA staining revealed that (E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol dose-dependently inhibited tumor growth, and the expression level of Fas, DR3, active caspase-3 was increased while the expression level of phosphor-STAT3 and p50 was decreased in nude mice xenograft tissues (Figure 6D).