In fact, hyperglycemia-induced monocyte adhesion to cultured aortic ECs in vitro by NF-κB activation increased the expression of pro-inflammatory genes and endothelial adhesion molecules, in particular vascular cell adhesion molecule 1 (VCAM-1) and monocyte chemoattractant protein-1 (MCP-1) [29,30]. This evidence concerns the gene VCAM1 and Hyperglycemia.