Furthermore, given that Th2-cell polarization in humans is thought to be one of the main mechanisms of action of GA [4,8,10,17] and that many factors (including IL-4, IL-5, IFN-γ, and IL-10) observed to be stimulated in the system under study are also observed to be modulated by GA in humans [6,17], the Th2-polarized T cell experiment system used in this study is relevant to the mechanisms observed in humans for the treatment of relapsing forms of MS with GA. The gene discussed is IFNG; the disease is myeloid sarcoma.