The sensitivity and specificity of MRP14 for discriminating ICC from IHBD, BilIN1, BilIN2, BilIN3, and IPNB were 0.8846 and 0.8000, 0.8341 and 0.7083, 0.6370 and 0.7780, 0.5962 and 1.0000, and 0.7716 and 0.8333, respectively. This evidence concerns the gene S100A9 and intrahepatic cholangiocarcinoma.