However, after controlling affect factors including age, sex, tumor location, tumor size/diameter, differentiation, invasion (T stages), lymphatic metastasis (N stages), venous invasion, and PNI, the multivariate analysis further confirmed that tumor size persisted to be significantly correlated to HNF1A-AS1 expression (p = 0.005), which meant that patients with tumor size ≥5 cm had lower levels of HNF1A-AS1. This evidence concerns the gene HNF1A and neoplasm.