TP53 and neoplasm: The proposed targets for miR-934 are also potent tumor suppressors: HOXA4 has been shown to inhibit cell motility and invasion in ovarian carcinoma [38]; MLL3 is involved in a p53 coactivator complex, with knockout resulting in epithelial tumor formation in mice [39]; and HIPK2 mediates apoptosis and activates p53 via phosphorylation at Ser46 [40].