JAK2 and myeloproliferative disorder: We treated MPN model cell lines, including JAK2-V617F-positive HEL, Uke1, and SET2 cells, and BAF3 cells that are transformed by the expression of JAK2-V617F (BaF3-JAK2-V617F), with AZD1208 and again saw little effect on cell growth and viability (Fig. 1B and not shown).