The repression of FBP1 reduced the volume and weight of the xenografts (Figures 7a and b, NC versus siFBP1, P=0.0029) The tumors obtained from injection of CNE2-NC/SiFBP1-1# were performed to assess the tumor pathology by HE staining (Figures 7c and d), FBP1 IHC staining (Figures 7e and f) and c-Myc IHC staining (Figure 7g and h), and then analyzed by a pathologist. Here, MYC is linked to neoplasm.