In addition, we also explored the function of the FBP1 protein in NPC cells using two independent small interference RNAs (siRNAs) to knock down the expression of FBP1, and found that silencing FBP1 suppresses cell proliferation, colony-formation abilities, side populations (SPs) and markedly reduces tumorigenesis in nude mice. Here, FBP1 is linked to nasopharyngeal carcinoma.