Tumor size of the cohort with STC1-High (mean 6.359) versus STC1-Normal (mean 7.841) was significantly reduced (p = 0.008), which was not associated with sex, age, tumor size with 5-cm cutoff, alpha fetoprotein level, hepatitis B surface-antigen level, metastasis stage, histological differentiation, infiltration, recurrence, and cirrhosis (Table 1). This evidence concerns the gene STC1 and Cirrhosis.