Particularly, a significant reduction in tumor sizes was shown in STC1/IL-8-High tumor (31% reduction versus STC1/IL-8-Normal, p = 0.025), but not in STC1/IL-6-High cases (22% reduction versus STC1/IL-6-Normal, p = 0.245), which may due to the small sample size of the STC1/IL-6-High cohort. The gene discussed is CXCL8; the disease is neoplasm.