DKK3 and lung carcinoma: Our current study revealed that forced expression of miR-582-3p in lung cancer cells might subject a subset of tumour cells to the pool of CSCs by causing simultaneous inhibition of AXIN2, DKK3 and SFRP1 and constitutive activation of the Wnt signalling pathway, thus promoting tumorigenesis and relapse of NSCLC xenografts.