After stimulation, more T cells express TH1 than TH2 cytokines in both the BALF and peripheral blood of sarcoidosis patients and more CD4+ T cells in BALF express TH1 receptors (CXCR3, CCR5, IL-12R and IL-18R) than CD4+ T cells in the peripheral blood. This evidence concerns the gene CD4 and sarcoidosis.