The study reports that severe hepatic steatosis was predicted by TCF (OR 2.2, CI 1.7 to 4.9) and grade 3 fibrosis was predicted by TCF (OR 2.0, CI 1.7 to 4.3); however, the analysis of histological characteristics is limited due to small sample size and because all patients had NASH. This evidence concerns the gene HNF4A and metabolic dysfunction-associated steatohepatitis.