Consistent with prior reports of differential usage of glutamine in mutant KRAS versus wild-type KRAS cancers [4, 8, 30, 38], we found that mutant KRAS cell lines, but not wild-type KRAS PDA, lung, and breast cancer, were sensitized to ß-lap upon pre-treatment with BPTES. The gene discussed is KRAS; the disease is Patent ductus arteriosus.