In patients with T1DM, higher concentrations of FGF-23 were positively associated with aPWV, even after adjusting for eGFR and classical cardiovascular risk factors (model 1: ß = 0.202, p = 0.026), other mineral metabolism parameters (model 2: ß = 0.214, p = 0.015), T1DM duration, microvascular complications, low-grade inflammation and ED (model 3: ß = 0.170, p = 0.045). The gene discussed is FGF23; the disease is type 1 diabetes mellitus.