Furthermore, the specific CD40+% for MDSC in tumor tissues (65.04% ± 6.71%, 50.56% ± 7.52% and 41.56% ± 6.69% from MFC-, LLC- and RM-1-injected mouse tumors, respectively) was significantly higher than the in the CD40+% in the spleen of the same mouse (p < 0.05; Figure 1). The gene discussed is CD40; the disease is neoplasm.