Then, we compared the mRNA levels of several TGF-β-related EMT-regulators including SNAI1, SNAI2, HMGA2, FOSL1, SP1, ZEB1, ZEB2 (SIP1), and TWIST1 [8, 32, 33] in primary tumor tissues of MDA-MB-231-xenografted mice. This evidence concerns the gene ZEB1 and neoplasm.