RAS protein activator like 2 (Rasal2) and ras homolog gene family, member J (RhoJ) showed a two-fold increase in expression in the pairwise comparisons of AOM-DSS-TSP-1-/- vs. water-TSP-1-/- and AOM-DSS-TSP-1-/- vs. AOM-DSS-WT (S1 Table).A comparison of the gene expression profiles of the WT mice, treated vs water, is presented in S2 Table. This evidence concerns the gene RASAL2 and infectious otitis media.