We confirmed strong ~10X sensitization of some, but not all, melanoma cells to vincristine with lapatinib, with a Bliss value > 50% and Combination Index (CI) of 0.37 [19] (Fig 2B and S3A and S3B Fig), and several other EGFR family member inhibitors including erlotinib (S3C Fig). Here, EGFR is linked to melanoma.