Known, validated targets for miR137 include the cell cycle regulator Cdc42 [7], estrogen related receptor ERRα/NR3B1 [12], p160 nuclear receptor coactivators [13] and the lysine specific demethylase 1 (KDM1A, LSD1), a transcriptional coregulator [6] which is over-expressed in many cancers [14 and references therein]. The gene discussed is ESRRA; the disease is cancer.