Furthermore, we analyzed the c-Kit (CD117) expression and, in accordance with the literature [33], we observed that melanoma cells with a strong metastatic potential, such as SKMEL28, MePA, MeTA and MV3, were negative for c-Kit expression, in contrast to MeMI that expressed c-Kit (Table 1, Supplementary Figure S1 B and S2) and was unable to form metastases. This evidence concerns the gene KIT and melanoma.