Using the minimum dose of the inhibitors required to completely inhibit their intended nodes (Supplemental Figure 1A), we confirmed that PI3K pathway suppression had little effect on viability in three GCB-DLBCL cell lines (OCI-LY1, OCI-LY8, SU-DHL4; Supplemental Figure 1B). The gene discussed is PIK3CD; the disease is diffuse large B-cell lymphoma.