Because β1 integrin inhibition reduces radiation survival independent of p53 status [7, 10], the downstream signaling of integrins, in particular the function of ILK, PINCH1 and ILKAP for the integrin-mediated radioresistance, seems to be different between p53-wildtype and p53-mutated GBM cell lines. Here, ILKAP is linked to glioblastoma.