AR and cancer: Additionally, several molecular studies have identified ATAD2A as a transcriptional co-regulator acting on cancer/proliferation-promoting factors such as oestrogen and androgen receptors (Zou et al., 2007, 2009), E2F transcription factors (Revenko et al., 2010) and Myc (Ciro et al., 2009; Boussouar et al., 2013).