High TILs value was not associated with certain clinical parameters of breast cancer, such as grade category (G1–2 vs. G3): (pooled RR 0.93, 95 % CI 0.77–1.13); hormone receptor status (+ vs. −): (pooled RR 0.48, 95 % CI 0.07–3.32); or HER-2 status (+ vs. −): (pooled RR 0.83, 95 % CI 0.61–1.12). Here, ERBB2 is linked to breast cancer.