Genes encoding transcriptional factor bHLH039, ZIP9, zinc binding protein (AT1G74770), ATROPGEF10, receptor like protein 24 RLP24, phloem protein 2-B6 and other functionally unknown proteins were among the second group of highly induced genes following Fe deficiency and were up-regulated by more than fivefold (Table 1; Fig. 2a, b). The gene discussed is RSL24D1; the disease is hyperinsulinemic hypoglycemia, familial, 4.