To evaluate if the anti-proliferative activity of tivantinib was due to inhibition of MET, we examined HCC cell lines that included two cell lines (MHCC97L and MHCC97H) with expression of p-MET and two HCC cells lines (Huh7 and HepG2) with negative expression of p-MET (Fig. 1a). Here, MET is linked to hepatocellular carcinoma.