ALDH1A1 and familial pancreatic carcinoma: However, patients with high expression levels of LC3 and ALDH1 simultaneously in pancreatic tumor cells demonstrated worse overall survival (OS) and disease-free survival (DFS) (P = 0.046 and P = 0.008; Fig. 1d), suggesting that coexpression of LC3/ALDH1 is a more specific prognostic marker for pancreatic cancer than is expression of either gene alone.