CASP8 and cervical cancer: However, the black Africans showed a marginal increased risk with CASP8 -652 6 N ins + FasR-1377G (P = 0.047, Combined Polymorphism Score (CPS) = 1.99) and cervical cancer and a reduced risk with CASP8 -652 6 N del + FasR-670A (P = 0.019, CPS = −2.34) with the same disease (CPS is similar as a haplotype score; a positive value suggests a positive association and a negative value suggests a negative association with the disease under investigation) (Table 2).