CD4 and type 2 diabetes mellitus: We had three main hypotheses: first, high levels of proinflammatory lymphocyte subpopulations, including γδ T and Th1 cells, would be positively associated with prevalent type 2 diabetes; second, that high levels of anti-inflammatory lymphocyte subpopulations including NK and Th2 cells, would be inversely associated with type 2 diabetes; and, third, a high degree of chronic adaptive immune activation, as characterized by higher memory and lower naive CD4+ T cells, would be positively associated with type 2 diabetes.