In the present study, CTRP9 and other adipokines were detected in the serum and EAT of CAD patients, and the relationship of circulating and coronary CTRP9 with the coronary atherosclerosis (CA) and its risk factors was further evaluated, which may elucidate whether the role of these factors in CAD is independent of APN. This evidence concerns the gene C1QTNF9 and coronary artery disorder.