LEP and coronary artery disorder: However, the serum levels of LDL-C, CRP, TNF-α, IL-6, and leptin in CAD patients were markedly higher than those in non-CAD patients (P < 0.05), and serum levels of APN and CTRP9 in CAD patients were dramatically lower than those in non-CAD patients (P = 0.021 and P = 0.005, resp).