KLF12 and neoplasm: KLF12 was initially identified as a repressor for the transcription factor AP-2α.18 Amplification of the chromosomal region 13q21-13q22 harbouring KLF12 occurs in salivary gland tumours19 and poorly differentiated gastric cancers have increased expression of KLF12 that correlate with tumour size,20 suggesting a possible oncogenic role.