In ipsilateral pair 12, the gains of chromosome 1q, part of 11q (including the cyclinD1 locus on11q13), 12p, part of 12q and 19 and losses of chromosome 6q, part of 11q, 12q and 13 were found in the primary tumour (Fig. 2a, b). This evidence concerns the gene CCND1 and neoplasm.