Results from Stevens et al. [30] and Hedberg et al. [31] demonstrated that B3GALNT2 is involved in the glycosylation of α-DG and that mutations within this gene can cause muscular dystrophy-dystroglycanopathy with muscle and brain anomalies. The gene discussed is B3GALNT2; the disease is neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan.