Our current results in cardiomyocyte H9c2 cells were consistent with previous studies demonstrating that at the senescence-inducing concentration (0.1 μM), DXR induced more DNA damage, as measured by phosphorylation of γ-H2A.X, (0.5 μM) than at the apoptosis-inducing concentration (1 μM) in human cervical carcinoma cells or other cells. The gene discussed is H2AX; the disease is cervical carcinoma.