Our IHC results show that the majority of tumor cells in SKOV3/pcDNA3.1-CTHRC1 xenografts expressed a more intense vimentin signal, but exhibited weaker E-cadherin staining, two key markers for tumor metastasis, indicating that these cells were undergoing the EMT process (Fig. 8C and 8D). The gene discussed is CTHRC1; the disease is neoplasm.