These results are in agreement with the findings of Varambally [17], where ST6GalNAc1 was found to be 4.43 fold over-expressed in localised prostate cancer versus benign tissue (p = 2.36E-006), but −5.9 fold under-expressed (p = 1.85E-007) in metastatic disease versus localised cancer; and are also consistent with a recent study where expression of ST6GalNAc1 was found to be 2.67 fold reduced in the progression to CRPCa (p = 1.55E13) [24]. This evidence concerns the gene ST6GALNAC1 and metastatic neoplasm.