However, multivariate analysis showed that high CHI3L1 expression (HR: 4.03, 95% CI: 2.37 − 6.87, p < 0.001), advanced stage (HR: 4.65, 95% CI: 1.41 − 15.31, p = 0.011) and residual tumor size > 1 cm after debulking surgery (HR: 2.95, 95% CI: 1.70 − 5.10, p < 0.001) were independent risk factors for death. This evidence concerns the gene CHI3L1 and neoplasm.