PDGFRA and glioblastoma: Distinct genomic aberrations including PDGFRA alterations and hotspot mutations in histone 3.3 (H3F3A) at codons 27 (K27) and 34 (G34) as well as histone 3.1 (HIST1H3B) at codon 27 (K27) were frequently found in glioblastomas in children [6–8].